Sterilization is a key technology in the field of medicine.There are many ways to sterilize, depending on the contact between the sterilizer and all surfaces of the object being treated.The type of reagent used depends on the nature of the item to be sterilized, and the time required to kill the harmful spores is critical.For heat-resistant and wet-resistant medical instruments, appliances and articles, should be selected pressure steam sterilization;Heat-resistant oils and dry powders should be sterilized by dry heat.For articles that are not heat-resistant or wet-resistant, it is advisable to adopt low-temperature sterilization methods such as ethylene oxide sterilization, hydrogen peroxide low-temperature plasma sterilization or low-temperature formaldehyde steam sterilization.
NASH ultra-quiet liquid ring vacuum pump is mainly designed for silent and clean industrial applications, such as hospitals/medical centers, laboratories, electronics factories, food, dairy products and other more clean applications, can achieve a balance between noise, performance and efficiency in operation.Global product design, suitable for 50/60hz operation, built-in mechanical seal leak free, noise as low as 66bB(A), efficiency up to 13%.NASH ultra-quiet vacuum pump keeps your sterilization system in a quiet operating environment.
No organism can survive direct exposure to saturated steam at 120℃ for more than 15 minutes.High temperature can eliminate microorganisms, while water ACTS in the form of steam to accelerate the sterilization effect, and pressure is crucial to improve the temperature of the sterilization steam.
The steam should penetrate into each fiber and reach every surface of the object to be sterilized.When steam enters the sterilizing chamber under pressure, it condenses when it comes into contact with cold objects. This releases heat, while room temperature and humidity increase, providing two important conditions for sterilization: moisture and heat.
The steam sterilization steps include:
Pretreatment - vacuum pump is used to empty all air and replace it with steam
Sterilization - heating objects by introducing steam and condensing it on all surfaces, heating and humidifying spores.
The post-treatment - sterilization process is completed at this stage, where the steam is emptied by applying a vacuum. This is often referred to as the drying stage, because in this process the condensate that evaporates is carried away by the vacuum pump.
Hydrogen peroxide plasma sterilization
In the process of hydrogen peroxide plasma sterilization, hydrogen peroxide is activated and produces reactive plasma or gas.Even at low concentrations and temperatures, the plasma cloud produces negative ions, electrons, and visible neutral-ion pores that quickly and efficiently kill microorganisms.
The steps involved include:
· the item to be sterilized is sealed in a vacuum chamber
· vacuum chamber air extraction
· generate gas discharge plasma
· vacuum chamber is injected with surfactant
· diffusion reagents
· extract part of the vacuum chamber gas
· generate active agent plasma
· remove gases or vapors from vacuum room items
· exhaust gas is discharged from the vacuum chamber
· vacuum chamber air extraction
· remove sterilized articles from the vacuum chamber
Ethylene oxide sterilization
Used to sterilize substances that may be damaged by high-temperature techniques such as pasteurization or autoclave.Ethylene oxide (EO) gas used as a gas shall be in direct contact with microorganisms on or in the object to be sterilized.Because EO is flammable and explosive in the air, it needs to be used in the explosion-proof sterilization room under controlled environment.In addition, the entire process takes longer than steam sterilization, typically 16 to 18 hours.
There are four main parameters affecting EO gas sterilization: ethylene oxide gas concentration, temperature, humidity, sterilization time.Each parameter is varied.The sterilizing chamber is heavily deoxygenated (to prevent explosion) and filled with EO gas and a mixture of supplementary gas.
EO gas sterilization depends on four parameters: EO gas concentration, temperature, humidity, and sterilization time, each of which can vary.Most of the oxygen in the sterilizing chamber is removed (to prevent an explosion) and then filled with a mixture of EO and other gases.
The basic steps are:
? vacuum it
? air intake
? post-pulse vacuum
Formaldehyde gas sterilization
Formaldehyde is used as a gaseous fumigant.Formaldehyde sterilization is more complicated and less efficient than other sterilization methods.Formaldehyde can be sterilized only if the vapor pressure damages the object to be sterilized and ethylene oxide and glutaraldehyde cannot be used.It has been discontinued in the United States, Canada and Australia, but is still in use in Europe and Asia.
Ozone is an allotrope of oxygen, and its sterilizing action is to destroy organic matter and inorganic matter directly by oxidation reaction.Ozone is an unstable gas that easily breaks down into oxygen.Ozone concentrations of 6 to 12 per cent flowed continuously through the vacuum chamber.Ozone penetration can be controlled by indoor vacuum or increased by increasing humidity.During the reaction, ozone breaks down to form oxygen molecules.Depending on the size and location of the vacuum chamber, the cycle time is 60 minutes.
In addition, after sterilization, it is necessary to dry the medical instruments in the sterilization cabinet to avoid the corrosion of the medical instruments caused by the steam condensate.NASH liquid ring vacuum pump can pump sterilization chamber faster than other diaphragm pumps, so that the product is drier.
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