Air, the speed of compression is relatively fast, and the gap between the punch and the die hole is relatively small. During compression, the air is not removed from the particles and is enclosed in the tablet. When there is no pressure, the air will expand, which will cause slivers.
According to the above situation, we should first make a pre-pressing device for the fine powder in the particles, so that the air may escape. However, many situations are unexplainable.
The tablet press will split when the pressure is relatively high. Reduce the pressure during tableting to prevent splitting. If the particles are too dry, splitting will occur, so the water content also plays a role in key role. The reason for the splitting of the tablet press is the improper compression of the particles, the elasticity of the particles is relatively strong, the elasticity of the pressed tablets is relatively high, and the uneven pressure will also be caused.
When the single-punch tablet presses the tablet, the tablet compression is relatively large. When the rotary tablet presses the tablet, the upper and lower compression of the tablet is relatively large. The size of the pressure is related to the elastic recovery rate of the tablet.
Yes, the elastic recovery rate of the upper and lower surfaces of the tablet is relatively high, and the upper surface of the tablet is moved out of the die hole first, so it cracks first.
The scientifically designed prescription can prevent the phenomenon of splitting, how to increase the plasticity of the auxiliary materials and the formability of the particles, and adding compressible starch in the process can solve the above problems.
During the compression process, the pressure reduction of the tablet press is less likely to cause splits, the recovery rate is also small, the compression time increases, and the plasticity also increases, which can prevent the phenomenon of splitting, and the amount of water content in the particles is acceptable.
Shape the plasticity of the particles, improve the distribution of pressure and prevent the phenomenon of splintering. A good amount of lubricant can also be added to change the pressure distribution and prevent splintering.
The above is the industry sharing about tablet presses, I hope everyone can like it.